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Kenneth Finnegan shared a tip on using 0603 SMDs on the .1″ perf board:
As a quick little tip, when I’m prototyping circuits on 0.1″ perf board, I like using 0603 surface mount components for all of my passives and LEDs, since they nicely fit between the pads. This way I don’t need to bother with any wiring between LEDs and their resistors, since I can just use three pads in a row to mount the LED and their corresponding current limiting resistor and just need to wire the two ends to where they’re going.
See the full post on his blog.